“Disco bacteria” could churn out drugs and useful chemicals
THE central idea of synthetic biology is that living cells can be programmed in the same way that computers can, in order to make them do things and produce compounds that their natural counterparts do not. As with computers, though, scientists need a way to control their creations. To date, that has been done with chemical signals. In a paper published in Nature Chemical Biology, Christopher Voigt, a biologist at the Massachusetts Institute of Technology, describes an alternative. Instead of chemicals, he and his colleagues demonstrate how to control customised cells with coloured light.
Engineering cells to respond to light is not a new idea. The general approach is called optogenetics, and it has become a popular technique for controlling nerve cells in neuroscience. But Dr Voigt is not interested in nerve cells. In 2005 he altered four genes in a strain of Escherichia coli bacteria, which gave…Continue reading
Source: Economist